Quinapril
Quinapril is an active ingredient of the class «ACE inhibitor».
An angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure
Boxed warning (US label)
Fetal toxicity. When pregnancy is detected, discontinue quinapril hydrochloride as soon as possible. Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
What it is used for
- Congestive heart failure
- Arterial hypertension
- Cardiovascular disease
- Diabetes
- Stroke
- Heart failure
- Kidney failure
Hypertension Quinapril tablets, USP are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
How it works
- Angiotensin-converting enzyme inhibitor
Class: ACE inhibitor
Common side effects
Hypertension Quinapril hydrochloride has been evaluated for safety in 4960 subjects and patients. Of these, 3203 patients, including 655 elderly patients, participated in controlled clinical trials.
Who should not take it
Quinapril tablets are contraindicated in patients who are hypersensitive to this product and in patients with a history of angioedema related to previous treatment with an ACE inhibitor.
Pregnancy and breastfeeding
Because quinapril hydrochloride is secreted in human milk, caution should be exercised when this drug is administered to a nursing woman.
Interactions
- Amiloride — hyperkalemia
- Bromocriptine — hyperinsulinism, hypotension
- Celecoxib — hyperkalemia, increased systemic arterial blood pressure, kidney failure
- Ciclosporin — hyperkalemia
- Diclofenac — hyperkalemia, increased systemic arterial blood pressure, kidney failure
- Furosemide — hypotension, orthostatic hypotension
- Hydrochlorothiazide — hypotension, decreased blood pressure
- Ibuprofen — hyperkalemia, increased systemic arterial blood pressure, kidney failure
- Indapamide — hypotension, decreased blood pressure
- Indometacin — hyperkalemia, kidney failure, increased systemic arterial blood pressure
- Irbesartan — syncope, acute kidney injury, hyperkalemia, kidney failure, hypotension
- Ketoprofen — increased systemic arterial blood pressure, hyperkalemia, kidney failure
- Losartan — syncope, hyperkalemia, kidney failure, acute kidney injury, hypotension
- Meloxicam — increased systemic arterial blood pressure, hyperkalemia, kidney failure
- Naproxen — increased systemic arterial blood pressure, hyperkalemia, kidney failure
- Piroxicam — increased systemic arterial blood pressure, kidney failure, hyperkalemia
- Spironolactone — hyperkalemia, hypotension
- Telmisartan — acute kidney injury, syncope, kidney failure, hyperkalemia, hypotension
- Trimethoprim — hyperkalemia
- Valsartan — hyperkalemia, acute kidney injury, hypotension, syncope, kidney failure
- Lithium carbonate
- Tetracycline
Brand names
United States
Accupril
Canada
Auro-Quinapril · Jamp Quinapril · Pms-Quinapril · Taro-Quinapril
Other trade names
Accupro · Quinil
Approval status
- US Food and Drug Administration
- prescription · since 1991
- Health Canada
- prescription · marketed
- First approval anywhere
- 1991
Codes
- ATC
- C09AA06
- RxNorm CUI
- 35208
- ChEMBL
- CHEMBL1592
- PubChem CID
- 40466957
- UNII
- RJ84Y44811
- Wikidata
- Q596022
Frequently asked questions
What is Quinapril used for?
Quinapril is used for: Congestive heart failure, Arterial hypertension, Cardiovascular disease, Diabetes, Stroke, Heart failure, and Kidney failure.
What kind of medicine is Quinapril?
Quinapril is an active ingredient of the class «ACE inhibitor».
What are the brand names of Quinapril?
Brand names of Quinapril include Accupril, Auro-Quinapril, Jamp Quinapril, Pms-Quinapril, Taro-Quinapril, Accupro, and Quinil.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- Health Canada Drug Product Database (Open Government Licence – Canada)