Riluzole
Riluzole is an approved active ingredient.
Medication used to treat amyotrophic lateral sclerosis
What it is used for
- Amyotrophic lateral sclerosis
TIGLUTIK is indicated for the treatment of amyotrophic lateral sclerosis (ALS). TIGLUTIK is indicated for the treatment of amyotrophic lateral sclerosis (ALS)
Rilutek is indicated to extend life or the time to mechanical ventilation for patients with amyotrophic lateral sclerosis (ALS).
How it works
- Sodium channel alpha subunit blocker
Common side effects
The following adverse reactions are described below and elsewhere in the labeling: Hepatic Injury Neutropenia Interstitial Lung Disease Pancreatitis Most common adverse reactions (incidence greater than or equal to 5% and greater than placebo) were oral hypoesthesia, asthenia, nausea, decreased lung function…
Who should not take it
TIGLUTIK is contraindicated in patients with a history of severe hypersensitivity reactions to riluzole or to any of its components (anaphylaxis has occurred).
Pregnancy and breastfeeding
There are no studies of riluzole in pregnant women, and case reports have been inadequate to inform the drug-associated risk. The background risk for major birth defects and miscarriage in patients with amyotrophic lateral sclerosis is unknown.
Interactions
Brand names
United States
Exservan · Rilutek · Tiglutik KIT
European Union
Rilutek · Riluzole Zentiva
Canada
Apo-Riluzole · Mylan-Riluzole · Rilutek
Other trade names
Teglutik
Approval status
- US Food and Drug Administration
- prescription · since 1995
- European Medicines Agency
- authorised · since 1996
- Health Canada
- prescription · marketed
- First approval anywhere
- 1995
Codes
- ATC
- N07XX02
- RxNorm CUI
- 35623
- ChEMBL
- CHEMBL744
- PubChem CID
- 5070
- UNII
- 7LJ087RS6F
- Wikidata
- Q415744
Frequently asked questions
What is Riluzole used for?
Riluzole is used for: Amyotrophic lateral sclerosis.
What are the brand names of Riluzole?
Brand names of Riluzole include Exservan, Rilutek, Tiglutik KIT, Riluzole Zentiva, Apo-Riluzole, Mylan-Riluzole, and Teglutik.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)