Sugammadex
Sugammadex is an active ingredient of the class «antidote».
Chemical compound
What it is used for
- Neuromuscular blockade
BRIDION ® is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide in adult and pediatric patients undergoing surgery.
Reversal of neuromuscular blockade induced by rocuronium or vecuronium. For the peadiatric population: sugammadex is only recommended for routine reversal of rocuronium-induced blockade in children and adolescents.
How it works
- Rocuronium sequestering agent
- Vecuronium sequestering agent
Class: antidote
Common side effects
The following serious adverse reactions are described elsewhere in the labeling: Anaphylaxis and Hypersensitivity Marked Bradycardia Most common adverse reactions (reported in ≥10% of adult patients at a 2, 4, or 16 mg/kg BRIDION dose and higher than the placebo rate): vomiting, pain, nausea, hypotension, and headache.
Who should not take it
BRIDION is contraindicated in patients with known hypersensitivity to sugammadex or any of its components.
Pregnancy and breastfeeding
There are no clinical trial data on BRIDION use in pregnant women to inform any drug-associated risks.
Interactions
Brand names
United States
Bridion
European Union
Bridion · Sugammadex Adroiq · Sugammadex Amomed · Sugammadex Fresenius Kabi · Sugammadex Mylan · Sugammadex Piramal
Canada
Bridion · Pms-Sugammadex · Teva-Sugammadex
Approval status
- US Food and Drug Administration
- prescription · since 2015
- European Medicines Agency
- authorised · since 2008
- Health Canada
- prescription · marketed
- First approval anywhere
- 2008
Codes
- ATC
- V03AB35
- RxNorm CUI
- 1726987
- ChEMBL
- CHEMBL2111107
- PubChem CID
- 6918584
- UNII
- ERJ6X2MXV7
- Wikidata
- Q420857
Frequently asked questions
What is Sugammadex used for?
Sugammadex is used for: Neuromuscular blockade.
What kind of medicine is Sugammadex?
Sugammadex is an active ingredient of the class «antidote».
What are the brand names of Sugammadex?
Brand names of Sugammadex include Bridion, Sugammadex Adroiq, Sugammadex Amomed, Sugammadex Fresenius Kabi, Sugammadex Mylan, Sugammadex Piramal, Pms-Sugammadex, and Teva-Sugammadex.
Medicines in the same class
- Alcohol
- Potassium iodide
- Sodium nitrite
- Methylene blue
- Acetylcysteine
- Naloxone
- Dimercaprol
- Fomepizole
- Thiosulfuric acid
- Hydroxocobalamin
- Pralidoxime
- Protamine sulfate
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)