Solifenacin

Solifenacin is an approved active ingredient.

Chemical compound

Informational only — not medical advice. Ask a doctor or pharmacist; never change a dose on your own.

What it is used for

Overactive bladder
Urinary incontinence
Polyuria
Urge incontinence

Solifenacin succinate tablets are indicated for the treatment of adults with overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.
US label

How it works

Muscarinic acetylcholine receptor M3 antagonist
Muscarinic acetylcholine receptor M2 antagonist

Common side effects

The most common adverse reactions (> 4% in solifenacin succinate tablets-treated patients and > placebo-treated patients) were dry mouth and constipation at both 5 mg and 10 mg doses; and urinary tract infection and blurred vision at the 10 mg dose.
US label

Who should not take it

Solifenacin succinate tablets are contraindicated in patients: • With urinary retention, • With gastric retention, • With uncontrolled narrow-angle glaucoma, and • Who have demonstrated hypersensitivity to solifenacin succinate or the inactive ingredients in…
US label

Pregnancy and breastfeeding

There are no studies with the use of solifenacin succinate in pregnant women to inform a drug-associated risk of major birth defects, miscarriages, or adverse maternal or fetal outcomes.

Excerpts from the US prescribing label (public domain), copied without changes.

Interactions

Mirabegron

Recorded interactions from open sources (Wikidata, US labels). The list is not complete — ask a pharmacist.

Brand names

United States

Vesicare · Vesicare LS

Canada

Ach-Solifenacin Succinate · Auro-Solifenacin · Bio-Solifenacin · Jamp Solifenacin Succinate · Pms-Solifenacin · Prz-Solifenacin · Sandoz Solifenacin · Taro-Solifenacin · Teva-Solifenacin · Vesicare

Approval status

US Food and Drug Administration: prescription · since 2004
Health Canada: prescription · marketed
First approval anywhere: 2004

Codes

ATC: G04BD08
ChEMBL: CHEMBL1734
PubChem CID: 154059
UNII: A8910SQJ1U
Wikidata: Q59575279

Frequently asked questions

What is Solifenacin used for?

Solifenacin is used for: Overactive bladder, Urinary incontinence, Polyuria, and Urge incontinence.

What are the brand names of Solifenacin?

Brand names of Solifenacin include Vesicare, Vesicare LS, Ach-Solifenacin Succinate, Auro-Solifenacin, Bio-Solifenacin, Jamp Solifenacin Succinate, Pms-Solifenacin, and Prz-Solifenacin.

Medicines in the same class

Sources and licences

ChEMBL (CC BY-SA 3.0)
Wikidata (CC0 1.0)
openFDA / DailyMed (public domain)
Health Canada Drug Product Database (Open Government Licence – Canada)

Updated November 15, 2026