Rizatriptan
Rizatriptan is an active ingredient of the class «antimigraine».
Chemical compound
What it is used for
- Migraine
RizaFilm™ is indicated for the acute treatment of migraine with or without aura in adults and in pediatric patients 6 to 17 years of age. Limitations of Use RizaFilm should only be used where a clear diagnosis of migraine has been established.
How it works
- Serotonin 1b (5-HT1b) receptor agonist
- Serotonin 1d (5-HT1d) receptor agonist
Class: antimigraine
Common side effects
The most common adverse reactions in adults were (incidence ≥5% and greater than placebo): asthenia/fatigue, somnolence, pain/pressure sensation, dizziness, and nausea To report SUSPECTED ADVERSE REACTIONS, contact Gensco Pharma at 1-866-608-6284 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch 6.1 Clinical Trials…
Who should not take it
RizaFilm is contraindicated in patients with: Ischemic coronary artery disease (angina pectoris, history of myocardial infarction, or documented silent ischemia), or other significant underlying cardiovascular disease.
Pregnancy and breastfeeding
Available human data on the use of rizatriptan in pregnant women are not sufficient to draw conclusions about drug-associated risk for major birth defects and miscarriage.
There are no data on the presence of rizatriptan or any active metabolites in human milk or on the effects of rizatriptan on the breastfed infant, or milk production.
Interactions
- Linezolid — geniospasm, hyperthermia, hypertension, mental status change
- Metoprolol
- Propranolol
Brand names
United States
Maxalt · Maxalt-Mlt
Canada
Accel-Rizatriptan ODT · ACT Rizatriptan · Ag-Rizatriptan ODT · Apo-Rizatriptan · Auro-Rizatriptan ODT · Bio-Rizatriptan ODT · Ipg-Rizatriptan · Jamp Rizatriptan · Jamp-Rizatriptan ODT · M-Rizatriptan · M-Rizatriptan ODT · Mar-Rizatriptan · Mar-Rizatriptan ODT · Maxalt · Maxalt RPD · Mylan-Rizatriptan ODT · Nat-Rizatriptan · Nb-Rizatriptan RDT · Nra-Rizatriptan ODT · Pms-Rizatriptan RDT
Approval status
- US Food and Drug Administration
- prescription · since 1998
- Health Canada
- prescription · marketed
- First approval anywhere
- 1998
Codes
- ATC
- N02CC04
- RxNorm CUI
- 88014
- ChEMBL
- CHEMBL905
- PubChem CID
- 5078
- UNII
- 51086HBW8G
- Wikidata
- Q212171
Frequently asked questions
What is Rizatriptan used for?
Rizatriptan is used for: Migraine.
What kind of medicine is Rizatriptan?
Rizatriptan is an active ingredient of the class «antimigraine».
What are the brand names of Rizatriptan?
Brand names of Rizatriptan include Maxalt, Maxalt-Mlt, Accel-Rizatriptan ODT, ACT Rizatriptan, Ag-Rizatriptan ODT, Apo-Rizatriptan, Auro-Rizatriptan ODT, and Bio-Rizatriptan ODT.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- Health Canada Drug Product Database (Open Government Licence – Canada)