Rasagiline
Rasagiline is an active ingredient of the class «dopaminergic».
Chemical compound
What it is used for
- Parkinson's disease
Rasagiline tablets are indicated for the treatment of Parkinson’s disease (PD). Rasagiline, a monoamine oxidase (MAO)-B inhibitor (MAOI), is indicated for the treatment of Parkinson’s disease
Azilect is indicated for the treatment of idiopathic Parkinson's disease (PD) as monotherapy (without levodopa) or as adjunct therapy (with levodopa) in patients with end-of-dose fluctuations.
How it works
- Monoamine oxidase B inhibitor
Class: dopaminergic
Common side effects
The following adverse reactions are described in more detail in the Warnings and Precautions section of the label: Hypertension Serotonin Syndrome Falling Asleep During Activities of Daily Living and Somnolence Hypotension / Orthostatic Hypotension Dyskinesia Hallucinations / Psychotic-Like Behavior Impulse Control…
Who should not take it
Rasagiline is contraindicated for use with meperidine, tramadol, methadone, propoxyphene, and MAO inhibitors (MAOIs), including other selective MAO-B inhibitors, because of risk of serotonin syndrome.
Pregnancy and breastfeeding
There are no adequate data on the developmental risks associated with the use of rasagiline in pregnant women.
Interactions
- Bupropion — hypertension
- Citalopram — hypertension, tachycardia, hyperthermia, mental status change, geniospasm
- Fluoxetine — hyperthermia, hypertension, mental status change, geniospasm, tachycardia
- Fluvoxamine — mental status change, tachycardia, geniospasm, hyperthermia, hypertension
- Levodopa — orthostatic hypotension
- Linezolid — hypertensive crisis, muscle stiffness, seizure, palpitation, headache disorder
- Paroxetine — tachycardia, hypertension, geniospasm, hyperthermia, mental status change
- Pethidine — toxicity
- Sertraline — hyperthermia, geniospasm, mental status change, hypertension
- Sumatriptan — mental status change, hyperthermia, geniospasm, hypertension
- Ciprofloxacin
- Dextromethorphan
- Dopamine
- Metoclopramide
- Norepinephrine
Brand names
European Union
Rasagiline ratiopharm · Rasagiline Viatris (previously Rasagiline Mylan)
Canada
Ag-Rasagiline · Apo-Rasagiline · Asn-Rasagiline · Jamp Rasagiline · Mint-Rasagiline · Teva-Rasagiline
Other trade names
Rasagiline mylan
Approval status
- US Food and Drug Administration
- prescription · since 2006
- European Medicines Agency
- authorised · since 2005
- Health Canada
- prescription · marketed
- First approval anywhere
- 2005
Codes
- ATC
- N04BD02
- RxNorm CUI
- 134748
- ChEMBL
- CHEMBL887
- PubChem CID
- 3052776
- UNII
- 003N66TS6T
- Wikidata
- Q420685
Frequently asked questions
What is Rasagiline used for?
Rasagiline is used for: Parkinson's disease.
What kind of medicine is Rasagiline?
Rasagiline is an active ingredient of the class «dopaminergic».
What are the brand names of Rasagiline?
Brand names of Rasagiline include Rasagiline ratiopharm, Rasagiline Viatris (previously Rasagiline Mylan), Ag-Rasagiline, Apo-Rasagiline, Asn-Rasagiline, Jamp Rasagiline, Mint-Rasagiline, and Teva-Rasagiline.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)