Nortriptyline
Nortriptyline is an active ingredient of the class «antidepressant».
Chemical compound
Boxed warning (US label)
Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other…
What it is used for
- Attention deficit hyperactivity disorder
- Neurotic disorder
- Anxiety disorder
- Pain
- Depressive disorder
- Depression
Pamelor™ (nortriptyline HCl) is indicated for the relief of symptoms of depression. Endogenous depressions are more likely to be alleviated than are other depressive states.
How it works
- Serotonin transporter inhibitor
- Norepinephrine transporter inhibitor
Class: antidepressant
Common side effects
Note – Included in the following list are a few adverse reactions that have not been reported with this specific drug. However, the pharmacologic similarities among the tricyclic antidepressant drugs require that each of the reactions be considered when nortriptyline is administered.
Who should not take it
Monoamine Oxidase Inhibitors (MAOIs) The use of MAOIs intended to treat psychiatric disorders with Pamelor or within 14 days of stopping treatment with Pamelor is contraindicated because of an increased risk of serotonin syndrome.
Interactions
- Bupropion
- Cimetidine
- Darunavir
- Dopamine
- Fluconazole
- Fluoxetine
- Paroxetine
- Procarbazine
- Rifampicin
- Sertraline
- Valproic acid
Brand names
United States
Aventyl · Aventyl Hydrochloride · Pamelor
Canada
Aventyl
Other trade names
Allegron · Motipress · Motival · Psychostyl
Approval status
- US Food and Drug Administration
- prescription · since 1964
- Health Canada
- prescription · marketed
- First approval anywhere
- 1964
Codes
- ATC
- N06AA10
- RxNorm CUI
- 7531
- ChEMBL
- CHEMBL445
- PubChem CID
- 4543
- UNII
- BL03SY4LXB
- Wikidata
- Q61387
Frequently asked questions
What is Nortriptyline used for?
Nortriptyline is used for: Attention deficit hyperactivity disorder, Neurotic disorder, Anxiety disorder, Pain, Depressive disorder, and Depression.
What kind of medicine is Nortriptyline?
Nortriptyline is an active ingredient of the class «antidepressant».
What are the brand names of Nortriptyline?
Brand names of Nortriptyline include Aventyl, Aventyl Hydrochloride, Pamelor, Allegron, Motipress, Motival, and Psychostyl.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- Health Canada Drug Product Database (Open Government Licence – Canada)