Mefenamic acid
Mefenamic acid is an active ingredient of the class «fenamates».
Chemical compound
Boxed warning (US label)
RISK OF SERIOUS CARDIOVASCULAR and GASTROINTESTINAL EVENTS Cardiovascular Thrombotic Events Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which…
What it is used for
- Premenstrual syndrome
- Hyperthermia
- Pain
- Rheumatism
- Dysmenorrhea
Mefenamic acid capsules are nonsteroidal anti-inflammatory drug indicated for: For management of mild to moderate pain in patient 14 years of age and older, when therapy will not exceed one week (7 days).
How it works
- Cyclooxygenase inhibitor
Class: fenamates
Common side effects
Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure In patients taking mefenamic acid or other NSAIDs, the most frequently reported adverse reactions occurring…
Who should not take it
Mefenamic acid capsules are contraindicated in the following patients: Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to mefenamic acid or any components of the drug product.
Pregnancy and breastfeeding
Use of NSAIDs, including mefenamic acid, can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
Interactions
- Aspirin
- Ciclosporin
- Diclofenac
- Digoxin
- Furosemide
- Indometacin
- Insulin human
- Lithium carbonate
- Meloxicam
- Methotrexate
- Norepinephrine
- Pemetrexed
- Propranolol
- Sodium citrate
- Warfarin
Brand names
United States
Ponstel
Other trade names
Contraflam · Dysman-250 · Dysman-500 · Meflam 250 · Meflam 500 · Mendys · Opustan 250 · Opustan 500 · Ponstan · Ponstan fte
Approval status
- US Food and Drug Administration
- prescription · since 1967
- Health Canada
- prescription · marketed
- First approval anywhere
- 1967
Codes
- ATC
- M01AG01
- RxNorm CUI
- 6693
- ChEMBL
- CHEMBL686
- PubChem CID
- 4044
- UNII
- 367589PJ2C
- Wikidata
- Q284321
Frequently asked questions
What is Mefenamic acid used for?
Mefenamic acid is used for: Premenstrual syndrome, Hyperthermia, Pain, Rheumatism, and Dysmenorrhea.
What kind of medicine is Mefenamic acid?
Mefenamic acid is an active ingredient of the class «fenamates».
What are the brand names of Mefenamic acid?
Brand names of Mefenamic acid include Ponstel, Contraflam, Dysman-250, Dysman-500, Meflam 250, Meflam 500, Mendys, and Opustan 250.
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- Health Canada Drug Product Database (Open Government Licence – Canada)