Lurasidone
Lurasidone is an active ingredient of the class «antipsychotics».
Chemical compound
Boxed warning (US label)
INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS; and SUICIDAL THOUGHTS AND BEHAVIORS WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS; and SUICIDAL THOUGHTS AND BEHAVIORS Elderly patients with…
What it is used for
- Anxiety
- Psychosis
- Mood disorder
- Schizoaffective disorder
- Bipolar disorder
- Schizophrenia
LATUDA is indicated for: Treatment of adult and adolescent patients (13 to 17 years) with schizophrenia. Monotherapy treatment of adult and pediatric patients (10 to 17 years) with major depressive episode associated with bipolar I disorder (bipolar depression).
Treatment of schizophrenia in adults aged 18 years and over.
How it works
- Serotonin 2a (5-HT2a) receptor antagonist
- Dopamine D2 receptor antagonist
Class: antipsychotics
Common side effects
Commonly Observed Adverse Reactions: The most common adverse reactions (incidence ≥ 5% and at least twice the rate of placebo) in patients treated with LATUDA were somnolence, akathisia, extrapyramidal symptoms, and nausea.
Who should not take it
Known hypersensitivity to lurasidone HCl or any components in the formulation. Angioedema has been observed with lurasidone. Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir, voriconazole, mibefradil, etc.).
Pregnancy and breastfeeding
Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to LATUDA during pregnancy.
Interactions
- Atazanavir
- Carbamazepine
- Clarithromycin
- Darunavir
- Diltiazem
- Erythromycin
- Fluconazole
- Phenytoin
- Rifampicin
- Ritonavir
- Verapamil
- Voriconazole
Brand names
Canada
Auro-Lurasidone · Jamp Lurasidone · Nra-Lurasidone · Pms-Lurasidone · Sandoz Lurasidone · Taro-Lurasidone
Approval status
- US Food and Drug Administration
- prescription · since 2010
- European Medicines Agency
- authorised · since 2014
- Health Canada
- prescription · marketed
- First approval anywhere
- 2010
Codes
- ATC
- N05AE05
- RxNorm CUI
- 1040028
- ChEMBL
- CHEMBL1237021
- PubChem CID
- 213046
- UNII
- 22IC88528T
- Wikidata
- Q416992
Frequently asked questions
What is Lurasidone used for?
Lurasidone is used for: Anxiety, Psychosis, Mood disorder, Schizoaffective disorder, Bipolar disorder, and Schizophrenia.
What kind of medicine is Lurasidone?
Lurasidone is an active ingredient of the class «antipsychotics».
What are the brand names of Lurasidone?
Brand names of Lurasidone include Auro-Lurasidone, Jamp Lurasidone, Nra-Lurasidone, Pms-Lurasidone, Sandoz Lurasidone, and Taro-Lurasidone.
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)