Leuprorelin
Leuprorelin is an approved active ingredient.
Chemical compound
What it is used for
- Prostatic hypertrophy
- Leiomyoma
- Precocious puberty
- Endometriosis
- Endometrial carcinoma
- Prostate cancer
- Infertility
- Ovarian cancer
- Breast cancer
- Prostate neoplasm
- Neoplasm
LUPRON DEPOT 7.5 mg for 1-month administration, 22.5 mg for 3-month administration, 30 mg for 4-month administration, and 45 mg for 6-month administration (leuprolide acetate) are indicated for the treatment of advanced prostate cancer.
Camcevi is indicated for the treatment of hormone dependent advanced prostate cancer and for the treatment of high-risk localised and locally advanced hormone dependent prostate cancer in combination with radiotherapy.
How it works
- Gonadotropin-releasing hormone receptor agonist
Common side effects
LUPRON DEPOT 7.5 mg for 1-month administration: The most common adverse reactions (>10%) were general pain, hot flashes/sweats, GI disorders, edema, respiratory disorder, urinary disorder.
Who should not take it
LUPRON DEPOT is contraindicated in: Hypersensitivity LUPRON DEPOT is contraindicated in individuals with known hypersensitivity to GnRH agonists or any of the excipients in LUPRON DEPOT. Reports of anaphylactic reactions to GnRH agonists have been reported…
Pregnancy and breastfeeding
Based on findings in animal studies and mechanism of action, LUPRON DEPOT may cause fetal harm when administered to a pregnant woman. There are no available data in pregnant women to inform the drug-associated risk.
Brand names
United States
Camcevi ETM · Camcevi KIT · Eligard KIT · Fensolvi KIT · Leuprolide Acetate FOR Depot Suspension · Lupron · Lupron Depot · Lupron Depot-Ped KIT · Viadur · Vobrig
Canada
Eligard · Lupron Depot · Zeulide Depot
Other trade names
Lupron depot-ped · Lupron depot ped
Approval status
- US Food and Drug Administration
- prescription · since 1985
- European Medicines Agency
- authorised · since 2022
- Health Canada
- prescription · marketed
- First approval anywhere
- 1985
Codes
- ATC
- L02AE02
- RxNorm CUI
- 42375
- ChEMBL
- CHEMBL1201199
- PubChem CID
- 657181
- UNII
- EFY6W0M8TG
- Wikidata
- Q907160
Frequently asked questions
What is Leuprorelin used for?
Leuprorelin is used for: Prostatic hypertrophy, Leiomyoma, Precocious puberty, Endometriosis, Endometrial carcinoma, Prostate cancer, Infertility, and Ovarian cancer.
What are the brand names of Leuprorelin?
Brand names of Leuprorelin include Camcevi ETM, Camcevi KIT, Eligard KIT, Fensolvi KIT, Leuprolide Acetate FOR Depot Suspension, Lupron, Lupron Depot, and Lupron Depot-Ped KIT.
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)