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Imiquimod

Imiquimod is an approved active ingredient.

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Chemical compound

Informational only — not medical advice. Ask a doctor or pharmacist; never change a dose on your own.

What it is used for

Imiquimod Cream, 3.75% is indicated for the topical treatment of clinically typical, visible, or palpable actinic keratoses (AK) of the face or balding scalp in immunocompetent adults.

US label

Imiquimod cream is indicated for the topical treatment of: External genital and perianal warts (condylomata acuminata) in adults. Small superficial basal cell carcinomas (sBCCs) in adults.

EMA

How it works

Common side effects

The following clinically significant adverse reactions are described elsewhere in the labeling: Local Skin Reactions Systemic Reactions Most common adverse reactions (≥4%) are local skin reactions (erythema, scabbing/crusting, flaking/scaling/dryness, edema, erosion/ulceration, exudate), headache, application site…

US label

Pregnancy and breastfeeding

Available data from case reports and case series have not established a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes when imiquimod is used during pregnancy.

Excerpts from the US prescribing label (public domain), copied without changes.

Brand names

United States

Aldara · Zyclara

European Union

Aldara · Zyclara

Canada

Aldara P · Taro-Imiquimod · Taro-Imiquimod Pump · Vyloma · Zyclara

Other trade names

Zartra

Approval status

US Food and Drug Administration
prescription · since 1997
European Medicines Agency
authorised · since 1998
Health Canada
prescription · marketed
First approval anywhere
1997

Codes

ATC
D06BB10
RxNorm CUI
59943
ChEMBL
CHEMBL1282
PubChem CID
57469
UNII
P1QW714R7M
Wikidata
Q423417

Frequently asked questions

What is Imiquimod used for?

Imiquimod is used for: Basal-cell carcinoma of the skin, Actinic keratosis, Anogenital venereal wart, Skin cancer, Common wart, Viral infectious disease, and Keratosis.

What are the brand names of Imiquimod?

Brand names of Imiquimod include Aldara, Zyclara, Aldara P, Taro-Imiquimod, Taro-Imiquimod Pump, Vyloma, and Zartra.

Medicines in the same class

Sources and licences

Updated November 15, 2026