Guanfacine
Guanfacine is an approved active ingredient.
Chemical compound
What it is used for
- Arterial hypertension
- Attention deficit hyperactivity disorder
INTUNIV ® is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) as monotherapy and as adjunctive therapy to stimulant medications.
Intuniv is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in children and adolescents 6 17 years old for whom stimulants are not suitable, not tolerated or have been shown to be ineffective.
How it works
- Adrenergic receptor alpha-2 agonist
Common side effects
The following serious adverse reactions are described elsewhere in the labeling: Hypotension, bradycardia, and syncope Sedation and somnolence Cardiac conduction abnormalities Rebound Hypertension Most common adverse reactions (≥5% and at least twice placebo rate) in fixed-dose monotherapy ADHD trials in children and…
Who should not take it
INTUNIV is contraindicated in patients with a history of a hypersensitivity reaction to INTUNIV or its inactive ingredients, or other products containing guanfacine.
Pregnancy and breastfeeding
Exposure Registry There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to ADHD medications, including INTUNIV, during pregnancy.
Interactions
- Amitriptyline — hypotension
- Diltiazem — hypotension
- Imipramine — hypotension
- Verapamil — hypotension
Brand names
European Union
Paxneury
Canada
Ag-Guanfacine XR · Apo-Guanfacine XR · Intuniv XR · Jamp Guanfacine XR · Pro-Guanfacine XR · Sandoz Guanfacine XR
Other trade names
Akfen · Estulic
Approval status
- US Food and Drug Administration
- prescription · since 1986
- European Medicines Agency
- authorised · since 2015
- Health Canada
- prescription · marketed
- First approval anywhere
- 1986
Codes
- ATC
- C02AC02
- RxNorm CUI
- 40114
- ChEMBL
- CHEMBL862
- PubChem CID
- 3519
- UNII
- 30OMY4G3MK
- Wikidata
- Q5613599
Frequently asked questions
What is Guanfacine used for?
Guanfacine is used for: Arterial hypertension and Attention deficit hyperactivity disorder.
What are the brand names of Guanfacine?
Brand names of Guanfacine include Paxneury, Ag-Guanfacine XR, Apo-Guanfacine XR, Intuniv XR, Jamp Guanfacine XR, Pro-Guanfacine XR, Sandoz Guanfacine XR, and Akfen.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)