Granisetron
Granisetron is an approved active ingredient.
Pharmaceutical drug
What it is used for
- Nausea
- Postoperative nausea and vomiting
- Neoplasm
- Vomiting
SUSTOL is indicated in combination with other antiemetics in adults for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic chemotherapy (MEC) or anthracycline and cyclophosphamide (AC) combination chemotherapy regimens.
Prevention of nausea and vomiting in patients receiving moderately or highly emetogenic chemotherapy, with or without cisplatin, for up to five consecutive days.
How it works
- Serotonin 3a (5-HT3a) receptor antagonist
Common side effects
The following clinically significant adverse reactions are described elsewhere in the labeling: Serious Injection Site Reactions Gastrointestinal Disorders Hypersensitivity Reactions Serotonin Syndrome Most common adverse reactions (≥ 3%) are injection site reactions, constipation, fatigue, headache, diarrhea…
Who should not take it
SUSTOL is contraindicated in patients with hypersensitivity to granisetron, any of the components of SUSTOL, or to any of the other 5-HT 3 receptor antagonists.
Pregnancy and breastfeeding
There are no available data on the use of SUSTOL in pregnant women. Limited published data on granisetron use during pregnancy are not sufficient to inform a drug-associated risk.
Interactions
Brand names
United States
Sancuso · Sustol
European Union
Sancuso
Canada
Apo-Granisetron · Nat-Granisetron
Other trade names
Granisetron hydrochloride preservative free · Granisol · Granisteron hydrochloride
Approval status
- US Food and Drug Administration
- prescription · since 1993
- European Medicines Agency
- authorised · since 2012
- Health Canada
- prescription · marketed
- First approval anywhere
- 1993
Codes
- ATC
- A04AA02
- RxNorm CUI
- 26237
- ChEMBL
- CHEMBL289469
- PubChem CID
- 3510
- UNII
- WZG3J2MCOL
- Wikidata
- Q596708
Frequently asked questions
What is Granisetron used for?
Granisetron is used for: Nausea, Postoperative nausea and vomiting, Neoplasm, and Vomiting.
What are the brand names of Granisetron?
Brand names of Granisetron include Sancuso, Sustol, Apo-Granisetron, Nat-Granisetron, Granisetron hydrochloride preservative free, Granisol, and Granisteron hydrochloride.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- European Medicines Agency (reuse with acknowledgement)
- Health Canada Drug Product Database (Open Government Licence – Canada)