Felodipine
Felodipine is an active ingredient of the class «calcium channel blocker».
Chemical compound
What it is used for
- Arterial hypertension
- Angina pectoris
- Cardiovascular disease
- Diabetes
Felodipine tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.
How it works
- Mineralocorticoid receptor antagonist
- Voltage-gated L-type calcium channel blocker
Class: calcium channel blocker
Common side effects
The most common clinical adverse events reported with felodipine administered as monotherapy at the recommended dosage range of 2.5 mg to 10 mg once a day were peripheral edema and headache.
Who should not take it
Felodipine is contraindicated in patients who are hypersensitive to this product.
Pregnancy and breastfeeding
: Pregnancy Category C. Teratogenic Effects- Studies in pregnant rabbits administered doses of 0.46, 1.2, 2.3, and 4.6 mg/kg/day (from 0.8 to 8 times** the maximum recommended human dose on a mg/m 2 basis) showed digital anomalies consisting of reduction in…
It is not known whether this drug is secreted in human milk and because of the potential for serious adverse reactions from felodipine in the infant, a decision should be made whether to discontinue nursing or to…
Interactions
- Erythromycin — tachycardia, water retention, flushing
- Carbamazepine
- Ceftazidime
- Cimetidine
- Efavirenz
- Fluconazole
- Metoprolol
- Phenobarbital
- Phenytoin
- Posaconazole
Brand names
United States
Plendil
Canada
Apo-Felodipine · Plendil · Sandoz Felodipine
Other trade names
Cabren · Cardioplen xl · Felogen xl · Felotens xl · Folpik xl · Keloc sr · Neofel xl · Parmid xl · Pinefeld xl · Preslow · Vascalpha
Approval status
- US Food and Drug Administration
- prescription · since 1991
- Health Canada
- prescription · marketed
- First approval anywhere
- 1991
Codes
- ATC
- C08CA02
- RxNorm CUI
- 4316
- ChEMBL
- CHEMBL1480
- PubChem CID
- 3333
- UNII
- OL961R6O2C
- Wikidata
- Q420644
Frequently asked questions
What is Felodipine used for?
Felodipine is used for: Arterial hypertension, Angina pectoris, Cardiovascular disease, and Diabetes.
What kind of medicine is Felodipine?
Felodipine is an active ingredient of the class «calcium channel blocker».
What are the brand names of Felodipine?
Brand names of Felodipine include Plendil, Apo-Felodipine, Sandoz Felodipine, Cabren, Cardioplen xl, Felogen xl, Felotens xl, and Folpik xl.
Medicines in the same class
Sources and licences
- ChEMBL (CC BY-SA 3.0)
- Wikidata (CC0 1.0)
- openFDA / DailyMed (public domain)
- Health Canada Drug Product Database (Open Government Licence – Canada)